Department of Oral Medicine and Periodontology

Faculty of Dental Sciences

Faculty of Dental Sciences

University of Peradeniya

Prof HNS Soyza

Professor in Pharmacology



Official Address :

Department of Oral Medicine and Periodontology
Faculty of Dental Sciences,
University of Peradeniya,
Peradeniya,
Sri Lanka


Email :

niroshanis@pdn.ac.lk


Telephone :

+94-081-2397470


Personal Website :






Professor in Pharmacology, Department of Oral Medicine & Periodontology

    PhD – Tokyo Medical and Dental University, Tokyo, Japan
    BDS – Faculty of Dental Sciences, University of Peradeniya, Sri Lanka
    Senior lecturer at Division of Pharmacology
  • President’s awards for scientific publication (2013)
  • Travel award – To present at International Association for Dental Research (IADR) by University of Peradeniya (2013)
  • NRC merit award for scientific publication (2011 and 2010)
  • Unilever/Hatton Award - International Association for Dental Research (IADR), Barcelona, Spain - 1st place in Senior- Basic category (2010)
  • IADR/Unilever Hatton Divisional Award (2010)
  • Asia Pacific Dental Congress (APDC) - 1st place in Free paper competition (2010)
  • JSPS Post-doctoral Fellowship (2009-2010) - Section of Pharmacology, Tokyo Medical and Dental University, Japan.Pre-doctoral Super student Fellowship (2007-2008) - Center of excellence, Tokyo Medical and Dental University, Japan.Travel award – International Conference on Osteoimmunology, Rhodes, Greece (2008)

    Visiting lecturer at Allied Health Sciences, University of Peradeniya
    Role of Rel B in bone homeostasis and osteoclastogenesis
    Feasibility of using NF-B inhibitors on bone formation
    Effect of fluoride on teeth and bone especially related to osteoporosis
    Complementary and alternative medicine


    --Research Profile--
  • Osteoclast function and bone-resorbing activity: An overview. Soysa NS, Alles N. BBRC.2016;476:115-120.

  • A Pilot Study on Attitudes, Knowledge and Behaviour Towards Dental Diseases Among Grade Medical Officers in the Kandy District, Sri Lanka N. S. Soysa1, and N. Alles. The Journal of Dentist, 2016, 4, 9-16

  • The local administration of TNF-α and RANKL antagonist peptide promotes BMP-2-induced bone formation.AbdullaAl MasudKhan,Neil Alles,NiroshaniS. Soysa,Kenichi Nagano,Risako Mikami,Yuri Furuya, Hisataka Yasuda, ,Kazuhiro Aoki. Journal of Oral Biosciences.2013; 55:47-54.

  • Peptide-based delivery to bone. Aoki K, Alles N, Soysa N, Ohya K. Adv Drug Deliv Rev. 2012 Sep;64(12):1220-38.

  • Osteoclast formation and differentiation: An overview. Soysa NS, Alles N, Aoki K, Ohya K. J Med Dent Sci. 2012 ;59:65-74.

  • Defective NIK in aly/aly mice prevents bone resorption induced by local injection of Lipopolysaccharide.  *Soysa NS, Alles N, Aoki K, Ohya K. J Perio Res. 2011;46(2):280-4. (Impact factor 1.990 in 2012).

  • *Received a commendation from Target Intelligence Service (TIS), a database used by pharmaceutical companies worldwide to identify ground breaking research of relevance to their own work on potential drug targets.
  • Suppression of NF-kappaB increases bone formation and ameliorates osteopenia in ovariectomized mice.Alles N, *Soysa NS, Hayashi J, Khan M, Shimoda A, Shimokawa H, Ritzeler O, Akiyoshi K, Aoki K, Ohya K. Endocrinology. 2010;151(10):4626-34. (Impact factor 4.717 in 2012).

  • The Pivotal Role of the Alternative NF-kappaB Pathway in Maintenance of Basal Bone Homeostasis and Osteoclastogenesis. Soysa NS, Alles N, Weih D, Lovas A, Mian AH, Shimokawa H, Yasuda H, Weih F, Jimi E, Ohya K, Aoki K. J Bone Miner Res. 2010;25(4):809-18. (Impact factor 6.128 in 2012). **Received a commendation from Faculty of 1000 which is an award-winning online service that highlights and evaluates the most interesting papers published in the biological sciences.

  • The Importance of Knowing the Patient’s Clotting Profile before Dental Treatment N.A. Alles, N.S. Soysa. Sri Lanka Dental Journal 2016; 46(01) 05-13

  • Histomorphometric Analysis Reveals Late Onset Increased Bone Mineral Density and Reduced Bone Resorption Indices in Tibiae in a Single-LPS Injection Murine Model N.S. Soysa, N. Alles, K. Aoki, K.Ohya Sri Lanka Dental Journal 2015; 45(03) 96-102

  • Computer-controlled local anesthetic delivery (CCLAD) and advanced injection techniques in dental armamentarium. Sri Lanka Dental Journal, 2014.

  • Pharmacological management of acute and postoperative pain in dental practice. Sri Lanka Dental Journal, 2012.