Faculty of Dental Sciences

University of Peradeniya

Faculty of Dental Sciences

University of Peradeniya

Dr KSND Gunawardhana

Senior Lecturer in Biochemistry



Official Address :

Department of Basic Sciences
Faculty of Dental Sciences,
University of Peradeniya,
Peradeniya,
Sri Lanka


Email :

nlk_gunawardhana@yahoo.com


Telephone :

+94-081-2397551


Personal Website :






Information on Research & Innovations


  • Niluka Gunawardhana, Sungil Jang, Yun Hui Choi, Youngmin A Hong, Yeong-Eui Jeon, Aeryun Kim, Hanfu Su, Ji-Hye Kim, Yun-Jung Yoo, D Scott Merrell, Jinmoon Kim, Jeong-Heon Cha. Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway. Frontiers in cellular and infection microbiology. 15; 7: 541: 2018.
  • Sungil Jang, Hanfu Su, Faith C Blum, Sarang Bae, Yun Hui Choi, Aeryun Kim, Youngmin A Hong, Jinmoon Kim, Ji-Hye Kim, Niluka Gunawardhana, Yeong-Eui Jeon, Yun-Jung Yoo, D Scott Merrell, Linhu Ge, Jeong-Heon Cha. Dynamic expansion and contraction of cagA copy number in Helicobacter pylori impact development of gastric disease, mBio. 8 (1) e01779-16: 2017.
  • Jinmoon Kim, Sungil Jang, Aeryun Kim, Hanfu Su, Niluka Gunawardhana, Yeong-Eui Jeon, Eun Jung Bak, Ji- Hye Kim, Jeong-Heon Cha. Role of bacterial γ-glutamyltranspeptidase as a novel virulence factor in bone-resorbing pathogenesis. Journal of Microbiology. 54: 5: 396-402: 2016.
  • Jinwook Lee, Niluka D Gunawardhana, Sungil Jang, Yun Hui Choi, Rasika P Illeperuma, Aeryun Kim, Hanfu Su, Youngmin A Hong, Ji-Hye Kim, Jinmoon Kim, Da-Woon Jung, In-Ho Cha, Eun-Jung Bak, Jeong-Heon Cha. Effect of Areca Nut on Helicobacter pylori-Induced Gastric Diseases in Mice. J Microbiol Biotechnol. 26 (10):1817-1823. 2016.
  • G.R. A.I. Rathnayake, B.G.T.L. Nandasena, N.D. Gunawardhana, K. Kita, M.P. Paranagama. Antioxidant and cytotoxic effects of a traditional polyherbal mouthwash on human gingival fibroblasts. 6th conference on Sri Lanka- Japan collaborative research 2018, p 50.
  • Niluka Gunawardhana, Jinmoon Kim, Yun Hui Choi, Sungil Jang, Yeong-Eui Jeon, Aeryun Kim, Jeong-Heon Cha. A EGF receptor ligand, HB-EGF plays a critical role in induction of gastrin expression during Helicobacter pylori pathogenesis. Gut Microbiota, Metabolic Disorders and Beyond. April 2016.
  • K. S. N. D. Gunawardhana, B. Navaratnam, G. K. Ranaweera, R. D. Jayasinghe, A. H. M. K. Abeysinghe. A descriptive analysis and clinical outcome of patients presented with lower impacted third molars to the District General Hospital- Nuwara Eliya. Proceedings of Peradenya University International Research Sessions (iPURSE 2016) 20; 224. 2016.
  • Yun Hui Choi, Aeryun Kim, Niluka Darshani Gunawardhana, Hanfu Su, Jinmoon Kim, Jeong-Heon Cha. Involvement of CagL polymorphisms between East-Asian and Western Helicobacter pylori in IL-8 induction. 14th Annual meeting of the Korean basic dental science society association 2015: 75.
  • Y. Choi, A. Kim, N. Gunawardhana, H. Su, J. Kim, J-H Cha. Investigation of Helicobacter pylori CagL polymorphisms between East-Asian and Western populations. American Society for Microbiology- 115th General Meeting 2015.
  • S. Jang, N. Gunawardhana, J. Kim, Y. Choi, Y-E. Jeon, A. Kim, D.S.Merrell, J-H. Cha. Helicobacter pylori promotes Gastrin promoter activity via HB-EGF, the EGF receptor, C-raf, Mek-1, and Erk2 in the Erk pathway. American Society for Microbiology- 115th General Meeting 2015.
  • Sungil Jang, Niluka Gunawardhana, Jinmoon Kim, Yun Hui Choi, Yeong-Eui Jeon, Aeryun Kim, D, Scott Merrell, Jeong-Heon Cha. Involvement of HB-EGF, the EGF receptor, C-Raf, Mek-1, and Erk2 in Helocobacter pylori-induced Gastrin promoter activation. International meeting of the microbiological society of Korea. April 2015.
  • “Effect of traditional anticariogenic herbal medicines in Sri Lanka on virulence gene expression of Streptococcus mutans”. University research grant in 2018.
  • “Comparative analysis of the total phenolic content and antioxidant capacity of Ocimum tenuiflorum in wet and dry zone of Sri Lanka”. Department of medical laboratory science, Faculty of allied health sciences, University of Peradeniya, Nethmini KPA (AHS/13/MLS/041)